Product name: |
Vinculin Rabbit pAb |
Reactivity: |
Human, Rat, Mouse |
Alternative Names: |
CMD1W antibody, CMH15 antibody, metavinculin antibody, MVCL antibody, VINC antibody |
Source: |
Rabbit |
Dilutions: |
WB 1:1,000-2,000 IHC 1:200-500 |
Immunogen: |
Synthetic Peptide |
Storage: |
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
Clonality: |
Polyclonal |
Isotype: |
IgG |
Concentration: |
1mg/mL |
Observed Band: |
130kDa |
GeneID: |
7414 |
Human Swiss-Prot No: |
P18206 |
Cellular localization: |
Cytoplasm,Cytoskeleton,Cell junction, Adherens junction |
Background: |
Vinculin is a membrane-cytoskeletal protein in focal adhesion plaques that is involved in linkage of integrin adhesion molecules to the actin cytoskeleton. Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. |